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rnf34 antibody  (Bio-Techne corporation)


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    Bio-Techne corporation rnf34 antibody
    Rnf34 Antibody, supplied by Bio-Techne corporation, used in various techniques. Bioz Stars score: 94/100, based on 4 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/rnf34 antibody/product/Bio-Techne corporation
    Average 94 stars, based on 4 article reviews
    rnf34 antibody - by Bioz Stars, 2026-02
    94/100 stars

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    (A) <t>RNF34</t> mRNA expression is significantly higher in RCC compared to NAT (p < 0.001). (B) Sequentially higher expression levels were found in more advanced tumor stages (p < 0.001). (C, D) Increased mRNA levels of RNF34 are associated with nodal-positive and metastatic disease (p = 0.04 and p < 0.001). (E-G) RNF34 mRNA expression was associated with a shortened progression-free, overall, and disease-specific survival (each Log-rank p < 0.001). Expression was dichotomized using the median as the cut-off value. p < 0.05 was considered as significant. RCC: renal cell carcinoma; ccRCC: clear cell renal cell carcinoma; TCGA: The Cancer Genome Atlas; NAT: normal adjacent tissue; PFS: progression-free survival; OS: overall survival; DSS: disease-specific survival.
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    (A) <t>RNF34</t> mRNA expression is significantly higher in RCC compared to NAT (p < 0.001). (B) Sequentially higher expression levels were found in more advanced tumor stages (p < 0.001). (C, D) Increased mRNA levels of RNF34 are associated with nodal-positive and metastatic disease (p = 0.04 and p < 0.001). (E-G) RNF34 mRNA expression was associated with a shortened progression-free, overall, and disease-specific survival (each Log-rank p < 0.001). Expression was dichotomized using the median as the cut-off value. p < 0.05 was considered as significant. RCC: renal cell carcinoma; ccRCC: clear cell renal cell carcinoma; TCGA: The Cancer Genome Atlas; NAT: normal adjacent tissue; PFS: progression-free survival; OS: overall survival; DSS: disease-specific survival.
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    (A) <t>RNF34</t> mRNA expression is significantly higher in RCC compared to NAT (p < 0.001). (B) Sequentially higher expression levels were found in more advanced tumor stages (p < 0.001). (C, D) Increased mRNA levels of RNF34 are associated with nodal-positive and metastatic disease (p = 0.04 and p < 0.001). (E-G) RNF34 mRNA expression was associated with a shortened progression-free, overall, and disease-specific survival (each Log-rank p < 0.001). Expression was dichotomized using the median as the cut-off value. p < 0.05 was considered as significant. RCC: renal cell carcinoma; ccRCC: clear cell renal cell carcinoma; TCGA: The Cancer Genome Atlas; NAT: normal adjacent tissue; PFS: progression-free survival; OS: overall survival; DSS: disease-specific survival.
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    (A) RNF34 mRNA expression is significantly higher in RCC compared to NAT (p < 0.001). (B) Sequentially higher expression levels were found in more advanced tumor stages (p < 0.001). (C, D) Increased mRNA levels of RNF34 are associated with nodal-positive and metastatic disease (p = 0.04 and p < 0.001). (E-G) RNF34 mRNA expression was associated with a shortened progression-free, overall, and disease-specific survival (each Log-rank p < 0.001). Expression was dichotomized using the median as the cut-off value. p < 0.05 was considered as significant. RCC: renal cell carcinoma; ccRCC: clear cell renal cell carcinoma; TCGA: The Cancer Genome Atlas; NAT: normal adjacent tissue; PFS: progression-free survival; OS: overall survival; DSS: disease-specific survival.

    Journal: Cureus

    Article Title: Ring Finger Protein 34 (RNF34) as a Prognostic Biomarker for Clear Cell Renal Cell Carcinoma

    doi: 10.7759/cureus.53038

    Figure Lengend Snippet: (A) RNF34 mRNA expression is significantly higher in RCC compared to NAT (p < 0.001). (B) Sequentially higher expression levels were found in more advanced tumor stages (p < 0.001). (C, D) Increased mRNA levels of RNF34 are associated with nodal-positive and metastatic disease (p = 0.04 and p < 0.001). (E-G) RNF34 mRNA expression was associated with a shortened progression-free, overall, and disease-specific survival (each Log-rank p < 0.001). Expression was dichotomized using the median as the cut-off value. p < 0.05 was considered as significant. RCC: renal cell carcinoma; ccRCC: clear cell renal cell carcinoma; TCGA: The Cancer Genome Atlas; NAT: normal adjacent tissue; PFS: progression-free survival; OS: overall survival; DSS: disease-specific survival.

    Article Snippet: The collected tissues were cut into 5 µm slices, mounted on slides, and stained using the specific polyclonal rabbit anti-RNF34 antibody in a 1:40 dilution (SAB2900260, Sigma-Aldrich, St. Louis, AZ).

    Techniques: Expressing

    Univariate and multivariate Cox regression analysis of RNF34 mRNA expression. * RNF34 mRNA expression was dichotomized based on the median. p < 0.05 was considered as significant.

    Journal: Cureus

    Article Title: Ring Finger Protein 34 (RNF34) as a Prognostic Biomarker for Clear Cell Renal Cell Carcinoma

    doi: 10.7759/cureus.53038

    Figure Lengend Snippet: Univariate and multivariate Cox regression analysis of RNF34 mRNA expression. * RNF34 mRNA expression was dichotomized based on the median. p < 0.05 was considered as significant.

    Article Snippet: The collected tissues were cut into 5 µm slices, mounted on slides, and stained using the specific polyclonal rabbit anti-RNF34 antibody in a 1:40 dilution (SAB2900260, Sigma-Aldrich, St. Louis, AZ).

    Techniques: Expressing

    Disease-specific survival in patients with ccRCC. Univariate and multivariate Cox regression analysis of RNF34 mRNA expression. * RNF34 mRNA expression was dichotomized based on the median. p < 0.05 was considered as significant. ccRCC: clear cell renal cell carcinoma.

    Journal: Cureus

    Article Title: Ring Finger Protein 34 (RNF34) as a Prognostic Biomarker for Clear Cell Renal Cell Carcinoma

    doi: 10.7759/cureus.53038

    Figure Lengend Snippet: Disease-specific survival in patients with ccRCC. Univariate and multivariate Cox regression analysis of RNF34 mRNA expression. * RNF34 mRNA expression was dichotomized based on the median. p < 0.05 was considered as significant. ccRCC: clear cell renal cell carcinoma.

    Article Snippet: The collected tissues were cut into 5 µm slices, mounted on slides, and stained using the specific polyclonal rabbit anti-RNF34 antibody in a 1:40 dilution (SAB2900260, Sigma-Aldrich, St. Louis, AZ).

    Techniques: Expressing

    (A) Staining patterns of RNF34 protein expression in different compartments: no expression, nuclear, cytoplasmic, and membranous expression; object magnification: 10x, scale bar: 50 µm. Both membranous (C) and nuclear (D) RNF34 protein expression were significantly associated with poor overall survival as determined by Kaplan-Meier estimates (membranous RNF34: log-rank p = 0.02, nuclear RNF34: log-rank p = 0.004). No impact of cytoplasmatic RNF34 expression on survival was evident (log-rank p = 0.07, B). The cut-off describing positive expression was set at ≥1. p < 0.05 was considered as significant. ccRCC: clear cell renal cell carcinoma; OS: overall survival.

    Journal: Cureus

    Article Title: Ring Finger Protein 34 (RNF34) as a Prognostic Biomarker for Clear Cell Renal Cell Carcinoma

    doi: 10.7759/cureus.53038

    Figure Lengend Snippet: (A) Staining patterns of RNF34 protein expression in different compartments: no expression, nuclear, cytoplasmic, and membranous expression; object magnification: 10x, scale bar: 50 µm. Both membranous (C) and nuclear (D) RNF34 protein expression were significantly associated with poor overall survival as determined by Kaplan-Meier estimates (membranous RNF34: log-rank p = 0.02, nuclear RNF34: log-rank p = 0.004). No impact of cytoplasmatic RNF34 expression on survival was evident (log-rank p = 0.07, B). The cut-off describing positive expression was set at ≥1. p < 0.05 was considered as significant. ccRCC: clear cell renal cell carcinoma; OS: overall survival.

    Article Snippet: The collected tissues were cut into 5 µm slices, mounted on slides, and stained using the specific polyclonal rabbit anti-RNF34 antibody in a 1:40 dilution (SAB2900260, Sigma-Aldrich, St. Louis, AZ).

    Techniques: Staining, Expressing

    Immunohistochemical analysis of RNF34 protein expression in ccRCC tissues and its association with clinicopathological parameters (chi-square test). p < 0.05 was considered as significant. ccRCC: clear cell renal cell carcinoma.

    Journal: Cureus

    Article Title: Ring Finger Protein 34 (RNF34) as a Prognostic Biomarker for Clear Cell Renal Cell Carcinoma

    doi: 10.7759/cureus.53038

    Figure Lengend Snippet: Immunohistochemical analysis of RNF34 protein expression in ccRCC tissues and its association with clinicopathological parameters (chi-square test). p < 0.05 was considered as significant. ccRCC: clear cell renal cell carcinoma.

    Article Snippet: The collected tissues were cut into 5 µm slices, mounted on slides, and stained using the specific polyclonal rabbit anti-RNF34 antibody in a 1:40 dilution (SAB2900260, Sigma-Aldrich, St. Louis, AZ).

    Techniques: Immunohistochemistry, Expressing

    Overall survival in patients with ccRCC. Univariate and multivariate Cox regression analysis of nuclear RNF34 expression. * RNF34 nuclear expression was dichotomized on positive vs. negative staining (immunohistochemistry). p < 0.05 was considered as significant. ccRCC: clear cell renal cell carcinoma.

    Journal: Cureus

    Article Title: Ring Finger Protein 34 (RNF34) as a Prognostic Biomarker for Clear Cell Renal Cell Carcinoma

    doi: 10.7759/cureus.53038

    Figure Lengend Snippet: Overall survival in patients with ccRCC. Univariate and multivariate Cox regression analysis of nuclear RNF34 expression. * RNF34 nuclear expression was dichotomized on positive vs. negative staining (immunohistochemistry). p < 0.05 was considered as significant. ccRCC: clear cell renal cell carcinoma.

    Article Snippet: The collected tissues were cut into 5 µm slices, mounted on slides, and stained using the specific polyclonal rabbit anti-RNF34 antibody in a 1:40 dilution (SAB2900260, Sigma-Aldrich, St. Louis, AZ).

    Techniques: Expressing, Negative Staining, Immunohistochemistry

    Progression-free survival in patients with ccRCC. Univariate and multivariate Cox regression analysis of membranous RNF34 expression. * RNF34 membranous expression was dichotomized on positive vs. negative staining (immunohistochemistry). p < 0.05 was considered as significant. ccRCC: clear cell renal cell carcinoma.

    Journal: Cureus

    Article Title: Ring Finger Protein 34 (RNF34) as a Prognostic Biomarker for Clear Cell Renal Cell Carcinoma

    doi: 10.7759/cureus.53038

    Figure Lengend Snippet: Progression-free survival in patients with ccRCC. Univariate and multivariate Cox regression analysis of membranous RNF34 expression. * RNF34 membranous expression was dichotomized on positive vs. negative staining (immunohistochemistry). p < 0.05 was considered as significant. ccRCC: clear cell renal cell carcinoma.

    Article Snippet: The collected tissues were cut into 5 µm slices, mounted on slides, and stained using the specific polyclonal rabbit anti-RNF34 antibody in a 1:40 dilution (SAB2900260, Sigma-Aldrich, St. Louis, AZ).

    Techniques: Expressing, Negative Staining, Immunohistochemistry